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2014 5
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2020 7
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Page 1
Diet, cardiovascular disease, and mortality in 80 countries.
Mente A, Dehghan M, Rangarajan S, O'Donnell M, Hu W, Dagenais G, Wielgosz A, A Lear S, Wei L, Diaz R, Avezum A, Lopez-Jaramillo P, Lanas F, Swaminathan S, Kaur M, Vijayakumar K, Mohan V, Gupta R, Szuba A, Iqbal R, Yusuf R, Mohammadifard N, Khatib R, Nasir NM, Karsidag K, Rosengren A, Yusufali A, Wentzel-Viljoen E, Chifamba J, Dans A, Alhabib KF, Yeates K, Teo K, Gerstein HC, Yusuf S. Mente A, et al. Eur Heart J. 2023 Jul 21;44(28):2560-2579. doi: 10.1093/eurheartj/ehad269. Eur Heart J. 2023. PMID: 37414411 Free PMC article.
During a median follow-up of 9.3 years in PURE, compared with a diet score of 1 points, a diet score of 5 points was associated with a lower risk of mortality [hazard ratio (HR) 0.70; 95% confidence interval (CI) 0.63-0.77)], CVD (HR 0.82; 0.75-0.91), myocardial inf …
During a median follow-up of 9.3 years in PURE, compared with a diet score of 1 points, a diet score of 5 points was associated with a lower …
Associations of fats and carbohydrate intake with cardiovascular disease and mortality in 18 countries from five continents (PURE): a prospective cohort study.
Dehghan M, Mente A, Zhang X, Swaminathan S, Li W, Mohan V, Iqbal R, Kumar R, Wentzel-Viljoen E, Rosengren A, Amma LI, Avezum A, Chifamba J, Diaz R, Khatib R, Lear S, Lopez-Jaramillo P, Liu X, Gupta R, Mohammadifard N, Gao N, Oguz A, Ramli AS, Seron P, Sun Y, Szuba A, Tsolekile L, Wielgosz A, Yusuf R, Hussein Yusufali A, Teo KK, Rangarajan S, Dagenais G, Bangdiwala SI, Islam S, Anand SS, Yusuf S; Prospective Urban Rural Epidemiology (PURE) study investigators. Dehghan M, et al. Lancet. 2017 Nov 4;390(10107):2050-2062. doi: 10.1016/S0140-6736(17)32252-3. Epub 2017 Aug 29. Lancet. 2017. PMID: 28864332
Higher carbohydrate intake was associated with an increased risk of total mortality (highest [quintile 5] vs lowest quintile [quintile 1] category, HR 1.28 [95% CI 1.12-1.46], p(trend)=0.0001) but not with the risk of cardiovascular disease or cardiovascular disease mortal …
Higher carbohydrate intake was associated with an increased risk of total mortality (highest [quintile 5] vs lowest quintile [quintile 1] ca …
Inflammatory Diseases, Inflammatory Biomarkers, and Alzheimer Disease: An Observational Analysis and Mendelian Randomization.
Huang J, Su B, Karhunen V, Gill D, Zuber V, Ahola-Olli A, Palaniswamy S, Auvinen J, Herzig KH, Keinänen-Kiukaanniemi S, Salmi M, Jalkanen S, Lehtimäki T, Salomaa V, Raitakari OT, Matthews PM, Elliott P, Tsilidis KK, Jarvelin MR, Tzoulaki I, Dehghan A. Huang J, et al. Neurology. 2023 Feb 7;100(6):e568-e581. doi: 10.1212/WNL.0000000000201489. Epub 2022 Nov 16. Neurology. 2023. PMID: 36384659 Free PMC article.
RESULTS: Cox regression models using CPRD data showed that the overall incidence of AD was higher among patients with inflammatory bowel disease (hazard ratio [HR] 1.17; 95% CI 1.15-1.19; p = 2.1 10(-4)), other inflammatory polyarthropathies and systematic connective tissu …
RESULTS: Cox regression models using CPRD data showed that the overall incidence of AD was higher among patients with inflammatory bowel dis …
Association of egg intake with blood lipids, cardiovascular disease, and mortality in 177,000 people in 50 countries.
Dehghan M, Mente A, Rangarajan S, Mohan V, Lear S, Swaminathan S, Wielgosz A, Seron P, Avezum A, Lopez-Jaramillo P, Turbide G, Chifamba J, AlHabib KF, Mohammadifard N, Szuba A, Khatib R, Altuntas Y, Liu X, Iqbal R, Rosengren A, Yusuf R, Smuts M, Yusufali A, Li N, Diaz R, Yusoff K, Kaur M, Soman B, Ismail N, Gupta R, Dans A, Sheridan P, Teo K, Anand SS, Yusuf S. Dehghan M, et al. Am J Clin Nutr. 2020 Apr 1;111(4):795-803. doi: 10.1093/ajcn/nqz348. Am J Clin Nutr. 2020. PMID: 31965140 Free PMC article. Clinical Trial.
In the PURE study, after excluding those with history of CVD, higher intake of egg (7 egg/wk compared with <1 egg/wk intake) was not significantly associated with blood lipids, composite outcome (HR: 0.96; 95% CI: 0.89, 1.04; P-trend = 0.74), total mortality (HR: …
In the PURE study, after excluding those with history of CVD, higher intake of egg (7 egg/wk compared with <1 egg/wk intake) was not sign …
Accelerated surgery versus standard care in hip fracture (HIP ATTACK): an international, randomised, controlled trial.
HIP ATTACK Investigators. HIP ATTACK Investigators. Lancet. 2020 Feb 29;395(10225):698-708. doi: 10.1016/S0140-6736(20)30058-1. Epub 2020 Feb 9. Lancet. 2020. PMID: 32050090 Clinical Trial.
The median time from hip fracture diagnosis to surgery was 6 h (IQR 4-9) in the accelerated-surgery group and 24 h (10-42) in the standard-care group (p<0.0001). 140 (9%) patients assigned to accelerated surgery and 154 (10%) assigned to standard care died, with a hazard ratio …
The median time from hip fracture diagnosis to surgery was 6 h (IQR 4-9) in the accelerated-surgery group and 24 h (10-42) in the standard-c …
Association of dairy intake with cardiovascular disease and mortality in 21 countries from five continents (PURE): a prospective cohort study.
Dehghan M, Mente A, Rangarajan S, Sheridan P, Mohan V, Iqbal R, Gupta R, Lear S, Wentzel-Viljoen E, Avezum A, Lopez-Jaramillo P, Mony P, Varma RP, Kumar R, Chifamba J, Alhabib KF, Mohammadifard N, Oguz A, Lanas F, Rozanska D, Bostrom KB, Yusoff K, Tsolkile LP, Dans A, Yusufali A, Orlandini A, Poirier P, Khatib R, Hu B, Wei L, Yin L, Deeraili A, Yeates K, Yusuf R, Ismail N, Mozaffarian D, Teo K, Anand SS, Yusuf S; Prospective Urban Rural Epidemiology (PURE) study investigators. Dehghan M, et al. Lancet. 2018 Nov 24;392(10161):2288-2297. doi: 10.1016/S0140-6736(18)31812-9. Epub 2018 Sep 11. Lancet. 2018. PMID: 30217460
No significant association with myocardial infarction was observed (HR 0.89, 95% CI 0.71-1.11; p(trend)=0.163). Higher intake (>1 serving vs no intake) of milk (HR 0.90, 95% CI 0.82-0.99; p(trend)=0.0529) and yogurt (0.86, 0.75-0.99; p(trend)=0.0051) was associat …
No significant association with myocardial infarction was observed (HR 0.89, 95% CI 0.71-1.11; p(trend)=0.163). Higher intake (>1 …
Fruit, vegetable, and legume intake, and cardiovascular disease and deaths in 18 countries (PURE): a prospective cohort study.
Miller V, Mente A, Dehghan M, Rangarajan S, Zhang X, Swaminathan S, Dagenais G, Gupta R, Mohan V, Lear S, Bangdiwala SI, Schutte AE, Wentzel-Viljoen E, Avezum A, Altuntas Y, Yusoff K, Ismail N, Peer N, Chifamba J, Diaz R, Rahman O, Mohammadifard N, Lana F, Zatonska K, Wielgosz A, Yusufali A, Iqbal R, Lopez-Jaramillo P, Khatib R, Rosengren A, Kutty VR, Li W, Liu J, Liu X, Yin L, Teo K, Anand S, Yusuf S; Prospective Urban Rural Epidemiology (PURE) study investigators. Miller V, et al. Lancet. 2017 Nov 4;390(10107):2037-2049. doi: 10.1016/S0140-6736(17)32253-5. Epub 2017 Aug 29. Lancet. 2017. PMID: 28864331 Free article.
The estimates were substantially attenuated in the multivariable adjusted models for major cardiovascular disease (hazard ratio [HR] 0.90, 95% CI 0.74-1.10, p(trend)=0.1301), myocardial infarction (0.99, 0.74-1.31; p(trend)=0.2033), stroke (0.92, 0.67-1.25; p(trend)=0.7092 …
The estimates were substantially attenuated in the multivariable adjusted models for major cardiovascular disease (hazard ratio [HR] …
Ultra-processed foods and mortality: analysis from the Prospective Urban and Rural Epidemiology study.
Dehghan M, Mente A, Rangarajan S, Mohan V, Swaminathan S, Avezum A, Lear SA, Rosengren A, Poirier P, Lanas F, Lopez-Jaramillo P, Soman B, Wang C, Orlandini A, Mohammadifard N, AlHabib KF, Chifamba J, Yusufali AH, Iqbal R, Khatib R, Yeates K, Puoane T, Altuntas Y, Co HU, Li S, Liu W, Zatońska K, Yusuf R, Ismail N, Miller V, Yusuf S; Prospective Urban Rural Epidemiology (PURE) study investigators. Dehghan M, et al. Am J Clin Nutr. 2023 Jan;117(1):55-63. doi: 10.1016/j.ajcnut.2022.10.014. Epub 2022 Dec 20. Am J Clin Nutr. 2023. PMID: 36789944 Free article.

We found a diet high in UPFs (2 servings/d compared with 0 intake) was associated with higher risk of mortality (HR: 1.28; 95% CI: 1.15, 1.42; P-trend < 0.001), CV mortality (HR: 1.17; 95% CI: 0.98, 1.41; P-trend = 0.04), and non-CV mortality (HR: 1.32; 95

…
We found a diet high in UPFs (2 servings/d compared with 0 intake) was associated with higher risk of mortality (HR: 1.28; 95% CI: 1. …
Severity of Disease and COVID-19 Complications During Hospital Stay: A Prospective Cohort Study.
Sami R, Soltaninejad F, Shayganfar A, Mirfendereski S, Mansourian M, Khademi N, Dehghan M, Khorrami Z, Jalali S, Mokhtari Z. Sami R, et al. Arch Iran Med. 2022 Jun 1;25(6):383-393. doi: 10.34172/aim.2022.62. Arch Iran Med. 2022. PMID: 35943018 Free article.
After adjustment for potential confounders, severity of the disease was positively associated with risk of mortality, invasive ventilation and ICU admissions (hazard ratio [HR]: 5.99; 95% CI: 2.85, 12.59; P<0.001, HR: 7.09; 95% CI: 3.24, 15.52; P<0.001 and …
After adjustment for potential confounders, severity of the disease was positively associated with risk of mortality, invasive ventilation a …
67 results